Salesforce releases six new AI agents for healthcare

Big Tech is moving full force ahead on healthcare AI.

On March 5, tech giant Salesforce announced the release of six new agentic AI tools for the medical industry. These agents will work on everything from referrals to identifying infectious disease patterns, per a press release. All tools will be under Agentforce Health, a library of AI software that the company launched in February 2025.

It’s also another example of a major tech company increasing its presence in healthcare as AI becomes more popular, as Amazon and Google have recently done.

“Our macro thesis is around how can we give time back to clinicians and reduce time in paperwork?” Amit Khanna, SVP and general manager for health and life sciences at Salesforce, told us.

Tool breakdown. The first three tools are for elevating “patient experience and accelerating care,” Khanna said. The next three, he said, “are more about operations and population disease management.”

• The first will work on routing referrals and assessments, looking through a patient’s electronic health records (EHRs) to find a specialist and book follow-up appointments.
• The second is a reading and writing agent that allows for a patient data exchange between different EHRs like Epic or Athenahealth. This can make it easier and quicker to add patients to new systems when interacting with new health systems and help them get medication refills, for example.
• The third tool will assist with health insurance claims and coverage so patients can interact with a chatbot at any time that has access to billing status, in-network providers, and medical and coverage information.
• The fourth tool will be an epidemiology analysis agent that public health agencies can use to detect infectious disease patterns.
• Fifth is a mobile app through AgentForce that works offline but still allows providers to see patient records and conduct appointments without connectivity. This is specifically designed to reach rural areas and help meet goals of the Center for Medicare and Medicaid’s new rural health initiative, which requires providers to send reports back to the federal government.
• Last, Salesforce created a hospital operations agent that’s meant to work like a “command center” to manage everything from staffing to equipment and help hospitals run smoothly.

Why healthcare? Khanna said Salesforce has been very interested in working in the healthcare industry over the last 10 years, making software appointment booking for providers and utilization management for payers. Its healthcare users include Chicago-based health system Rush and insurer Humana.

The tech company’s market cap has grown from $50.8 billion in March 2016 to $178.1 billion in February 2026.

Salesforce wants to work in healthcare, he said, because it has leading “metadata platform capability,” i.e., its technology is advanced enough to address operational problems in healthcare compared to some of the more outdated tech used in the industry. The company also has a lot of industry knowledge outside of healthcare that translates over, such as financial services work that may have statistics (like patient data from the EHR or insurance information) that could help identify healthcare needs, he added.

With this in mind, Khanna said the company can have a single platform that works “from the front to the back” office of the medical industry.

Tech takeover. This announcement is just the latest move from a Big Tech company into healthcare. Amazon, Microsoft, and Nvidia have all released new tools or announced new partnerships in recent months.

Atiq Bhatti, faculty administrator and clinical research operations lead at Old Dominion University’s department of medicine in Virginia, said in an email that Big Tech is interested in healthcare “because operational infrastructure health systems already exist outside of healthcare, and the market failure is too large to ignore.”

“These companies have already spent decades unifying fragmented data, automating multistep workflows, and scaling digital engagements across finance, logistics, and retail, and healthcare is the last major sector that has not undergone that transformation,” Bhatti added.