AI 411: November 2025

Welcome back to AI 411, a monthly roundup of AI announcements from across the healthcare industry.

This month, insurer Aetna, Minnesota-based health system Mayo Clinic, electronic health records (EHR) company Athenahealth, and New York-based health system Northwell Health made updates to their technology. There were also a couple of noteworthy fundraising rounds.

Here’s your breakdown of November AI updates from across the healthcare industry.

Abridge. Chicago-based UI Health finalized its expanded use of Abridge’s AI tools across its inpatient, outpatient, and emergency care offerings as of Nov. 24.

Aetna. Aetna, the insurance arm of CVS Health, announced Nov. 18 the launch of an AI assistant that can help members summarize benefits and ask questions about their plan.

Athenahealth. On Nov. 4, Athenahealth introduced an “AI-native clinical encounter” that aims to change the EHR from a simple documentation tool into an AI copilot by adding an AI scribe called athenaAmbient. User testing for the new product will start in the first half of 2026.

Hippocratic AI. Agentic company Hippocratic AI, which helps with care management and provider operations, announced a $126 million Series C on Nov. 3 led by venture capital (VC) firm Avenir Growth. The company’s total funding is now $404 million.

House Rx: On Nov. 12, House Rx raised $55 million in a Series B round led by VCs New Enterprise Associates and Town Hall Ventures. The company, which uses AI to make specialty medications more accessible, plans to expand its in-clinic speciality pharmacy model with the money. In total, the company has raised $100 million.

Mayo Clinic. On Nov. 3, Mayo Clinic launched Mayo Clinic Platform_Insights to allow other health systems to access its clinical and operational expertise “to reduce the digital divide” caused by AI.

Naples Comprehensive Health. Florida hospital system Naples Comprehensive Health, announced Nov. 5 it has become the first hospital in the country to use tech company Caristo Diagnostics’s AI imaging platforms CaRi-Plaque and CaRi-Heart to predict heart disease and heart attack risk up to 10 years before patients show symptoms.

No Barrier. No Barrier, which uses AI to help with medical translation, announced a $2.7 million seed funding round Nov. 17 led by VCs A-Squared Ventures, Esplanade Ventures, Rock Health Capital, and Fusion.

Northwell Health. On Nov. 20, Northwell Health announced a joint venture with K Health to integrate the health tech’s AI primary care platform, through which patients can chat with a personalized medical AI and schedule same-day appointments.

Popai Health. Voice AI company Popai Health, which pulls information from patient phone calls to help with care coordination, announced Nov. 3 a $11 million fundraising round led by VCs Team8 and New Enterprise Associates. The series was not disclosed.