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We spoke with the Cost Plus Drugs founder about PBMs, payers, pharma, and more.

Podcasts: Fun or stress inducing? Perhaps the latter if you’re startup founder (and owner of the Los Angeles Times) Patrick Soon-Shiong, who got into some hot water—meaning he received a warning letter from the FDA—last week after claiming his startup ImmunityBio’s cancer drug Anktiva can cure or prevent all cancers. What, like it’s a bad thing to set ridiculously high goals that have yet to be achieved in modern medicine? Sheesh.

In today’s edition:

Mark Cuban talks all things healthcare

Doc Dollywood

Bringing radiopharmaceuticals to the US

—Maia Anderson, Cassie McGrath, Tricia Crimmins

PHARMA

Mark Cuban at Billboard House @ SXSW

Getty Images

Despite coming up in the worlds of entrepreneurship and reality television, Mark Cuban has become a big name in the healthcare industry in recent years.

In 2022, the billionaire entrepreneur founded Mark Cuban Cost Plus Drug Company, an online pharmacy that skirts insurance and sells drugs at cost with a 15% markup and fee for pharmacy labor and shipping. The company also posts on its website exactly how much it paid manufacturers for the medicines it sells in an effort to boost transparency in a historically complex and opaque industry.

In a recent interview, Cuban told Healthcare Brew he became interested in disrupting the healthcare industry in 2017 when the first Trump administration was determined to “repeal and replace” Obamacare.

“Out of curiosity, I dug in and started getting involved with it and trying to look at ways to change the system, and come up with better approaches to health insurance and healthcare,” he said.

When Alex Oshmyansky, a radiologist who became co-founder and CEO of Cost Plus, sent Cuban an email pitching a compounding pharmacy to manufacture drugs on the FDA’s shortage list, Cuban said, “I thought, ‘OK, that’s cool, but that’s not big enough.’”

Find more nuggets of wisdom from Cuban here.—MA

From The Crew

HOSPITALS

Logo for Dolly Parton Children’s Hospital

Dolly Parton Children’s Hospital

Working 9-to-5 is getting a new meaning at Knoxville-based East Tennessee Children’s Hospital after it officially rebranded on Feb. 26.

While leadership declined to share the donation amount from the singer and actress, the newly named Dolly Parton Children’s Hospital launched, adding another badge to Parton’s long philanthropic history.

“Every child deserves world-class care, wrapped in kindness and love,” Parton said in a press release. “I’m so honored to stand alongside this hospital and do my part to help bring more hope, more comfort, and more healing to children and families.”

But the name change is more than just a new sign slapped on a building. Both a hospital executive and advertising expert told us the rebrand could bring more recognition, additional philanthropy, and possibly better care to the 152-bed independent hospital that serves 500,000 patients each year.

What’s in a name? Authencity, perhaps.—CM

MANUFACTURING

A medical practitioner looking at MRI results next to a graphic of the nucleus of atoms

Illustration: Brittany Holloway-Brown, Photos: Adobe Stock

As demand for radiopharmaceuticals and nuclear medicine increases, US-based producers are aiming to meet the moment.

Radiopharmaceuticals are radioactive treatments that can diagnose and treat cancer. One of the US’s largest manufacturers, Cardinal Health, announced today that it’s expanding its production of actinium-225, a radionuclide used for cancer treatment, at a facility in Indianapolis, Indiana. The news comes on the heels of last week’s announcement from Shine Technologies—one of Cardinal’s suppliers—that it is now exporting its own medical isotope, lutetium-177, from its production site in Wisconsin to China though Chinese radiopharmaceutical company C-Ray.

The US typically relies on overseas reactors for critical radiopharmaceuticals, something that the Trump administration has expressed a desire to change. In press releases for both announcements, Cardinal Health and Shine underscored the impact their latest advancements will have on the US radiopharmaceutical supply chain and increasing demand.

Here’s what Cardinal and Shine have planned.—TC

VITAL SIGNS

A laptop tracking vital signs is placed on rolling medical equipment.

Francis Scialabba

Today’s top healthcare reads.

Stat: $6.3 billion. That’s how much Eli Lilly will spend, at least initially, to acquire narcolepsy drug biopharma Centessa Pharmaceuticals. (the New York Times)

Quote: “The bar is very high, which, as a physician, I’m very happy about. As a scientist, trying to move this forward—it’s not frustrating, but it definitely poses a large initial hurdle.”—Rebecca Ahrens-Nicklas, associate chief for research with the division of human genetics at Children’s Hospital of Philadelphia, on FDA standards for developing custom gene-editing treatments (Stat)

Read: Researchers could only reproduce the results of about half of social sciences studies in a new project. (Science Magazine)

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