Abbott’s newest Infinity deep brain stimulation (DBS) system trial has begun.
On March 5, the Icahn School of Medicine at Mount Sinai announced that the first patient had officially been implanted with Abbott’s DBS system for a multisite, randomized controlled trial of the device’s effects on treatment-resistant depression.
The trial will follow this patient and others for the next three years, according to a Mount Sinai press release. In total, it aims to recruit about 100 participants who haven’t responded to four or more antidepressant treatments, according to the clinical trials government site. Half will have their implants turned on and half will not, with the two groups compared after the first year.
DBS systems like Infinity are used to adjust abnormal activity in areas of the brain that impact Parkinson’s and essential tremor through targeted electrical signals. In 2022, the FDA gave Abbott breakthrough device designation to investigate whether its system can treat treatment-resistant depression this way, too. On Sept. 4, Abbott announced this new trial.
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